The VIP terminal near the Odorna Market is reported to have been gutted in a massive fire.
Reports say many people have been left stranded in the area which is close to the Kwame Nkrumah Circle in Accra
About 4 fire tenders were at the scene to fight the fire.
It is not clear what caused the blaze. Some accounts have blamed an electrical short-circuit.
More than 5,000 buses operate in the multi-entrance terminal.
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